Digoxin interstage mortality
WebMar 6, 2024 · Patients with a serum digoxin concentration ≥1.2 ng/ml had a 56% increased hazard of mortality (adjusted HR, 1.56; 95% confidence interval [CI], 1.20–2.04). When analyzed as a continuous variable, serum digoxin concentration was associated with a 19% higher adjusted hazard of death for each 0.5 ng/ml increase (p = 0.0010); these results ... WebOct 1, 2024 · Interstage mortality is poorly understood and remains a high-risk period for patients with SVCHD. We present a validated risk score to predict interstage mortality that identified moderate or greater TR and a persistent supplemental O 2 requirement as the greatest risk subgroup. Interstage mortality may be impacted by intensifying …
Digoxin interstage mortality
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WebJan 13, 2016 · Background: Mortality for infants with single ventricle congenital heart disease remains as high as 8% to 12% during the interstage period, the time between … WebDec 1, 2024 · The impact of digoxin on interstage mortality remains unproven. Abstract. The use of Digoxin has been associated with improved interstage survival following …
WebJan 1, 2016 · Digoxin use in infants with single ventricle congenital heart disease is associated with significantly reduced interstage mortality, and the number needed to treat to prevent 1 death was 11 patients. Background Mortality for infants with single ventricle congenital heart disease remains as high as 8% to 12% during the interstage period, the … WebQuality improvement efforts have focused on reducing interstage mortality for infants with hypoplastic left heart syndrome (HLHS). In 1/2016, two publications reported that use of digoxin was associated with reduced interstage mortality. The degree to which these findings have affected real world pr …
WebApr 11, 2024 · cardiac function , digoxin , echocardiogram , interstage mortality , interstage period , single-ventricle congenital heart disease Search for Similar Articles … WebMay 4, 2024 · Effect of Digoxin on Interstage Outcomes following Stage I Palliation for Functionally Univentricular Hearts: A Systematic Review and Meta-Analysis May 2024 DOI: 10.1101/2024.05.04.22274522
WebMar 1, 2024 · Background Infants born with single right ventricle congenital heart disease (SVCHD) physiology, such as hypoplastic left heart syndrome and variants, are at a high risk for death or transplant during the interstage (IS) defined as the period between Stage 1 surgery (aorto-pulmonary shunt with arch reconstruction) and Stage 2 surgery (superior …
WebThe protective effect of digoxin for interstage mortality, despite an unclear therapeutic mechanism, has been reported in several studies [9, 17,32]. Based largely on these reports, the use of ... kontraindikation infusionstherapieWebInterstage mortality was 9.4%. Digoxin use was associated with lower risk of death (P =.03) on univariable analysis, however no single medication was an independent predictor on regression analysis. Change in weight-for-age z-score was studied as outcome of somatic growth with 36.3% patients showing a decrease during the interstage period. kontraindikationen psychotherapieWebFeb 2, 2024 · Quality improvement efforts have focused on reducing interstage mortality for infants with hypoplastic left heart syndrome (HLHS). In 1/2016, two publications reported that use of digoxin was associated with reduced interstage mortality. The degree to which these findings have affected real world practice has not been evaluated. The discharge … kontraindikation niv therapieWebJan 11, 2016 · Interstage mortality by surgical site (n=50 centers). This figure shows interstage mortality (IM) among the 544 infants in the … kontraindikation psychotherapieWebJan 26, 2016 · Interstage mortality for those not on digoxin was 12.3%, compared to 2.9% among those on digoxin, with an adjusted hazard ratio of 3.5 (95% CI, 1.1–11.7; … kontraindikation tracheostomaWebDigoxin has been associated with reduced interstage mortality after Norwood procedure. We sought to determine its association with survival and change in weight-for-age Z-score (WAZ) before the ... kontraindikation kompressionstherapieWebQuality improvement efforts have focused on reducing interstage mortality for infants with hypoplastic left heart syndrome (HLHS). In 1/2016, two publications reported that use of digoxin was associated with reduced interstage mortality. The degree to which these findings have affected real world practice has not been evaluated. kontraindikation physiotherapie