Exopolyphosphatase prune1
WebAug 15, 2016 · The prognosis of patients with colorectal liver metastases (CRLM) remains low despite advances in chemotherapy and surgery. The expression of h-prune (human homolog of Drosophila prune protein; HGNC13420), an exopolyphosphatase, is correlated with progression and aggressiveness in several cancers and promotes migration and … WebMar 21, 2024 · PRUNE1 prune exopolyphosphatase 1 Gene ID: 58497, updated on 4-Dec-2024 Gene type: protein coding Also known as: PRUNE; DRES17; HTCD37; NMIHBA; DRES-17; H-PRUNE See all available tests in GTR for this gene Go to complete Gene record for PRUNE1 Go to Variation Viewer for PRUNE1 variants Summary
Exopolyphosphatase prune1
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WebOct 22, 2024 · Thus, the crucial role of polyPs in cell metabolism is clear, as also confirmed in transgenic mice widely expressing the scPPX1 exopolyphosphatase that displayed a reduced mitochondrial respiration in muscles . Prune_1 Protein Interaction With Protein Binding Partners. Human Prune_1 is a naturally unfolded multi-domain adaptor protein. WebOct 26, 2024 · We note that the in vitro exopolyphosphatase activity of Prune is mostly against very short chains (3 to 4 phosphate units in length) (44, 62). In our experiments, Prune was also expressed at...
WebFeb 23, 2024 · PRUNE1 c.933G>A synonymous variant induces exon 7 skipping, disrupts the DHHA2 domain, and leads to an atypical NMIHBA syndrome presentation: Case … WebJul 1, 2013 · Description. Prune, a 62 kDa protein, belongs to the DHH family phosphoesterase proteins including RecJ DNA repair exonucleases, …
WebPrune1 Overexpression Constructs, supplied by OriGene, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ... (left panel). Short-chain exopolyphosphatase activity of wild type, D106N* and R128Q* mutants on P3 and P4 determined using fixed-time BIOMOL Green phosphate detection assay (middle and right … WebFeb 23, 2024 · PRUNE1 c.933G>A synonymous variant induces exon 7 skipping, disrupts the DHHA2 domain, and leads to an atypical NMIHBA syndrome presentation: Case report and review of the literature - Magyar - 2024 - American Journal of Medical Genetics Part A - Wiley Online Library Advanced Search Citation Search Advanced Search Citation …
Webexopolyphosphatase PRUNE1 protein prune homolog prune homolog PubChem 2 Organism-Specific Genes PRUNE1 - prune exopolyphosphatase 1 (human) Prune1 - …
WebThis protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants. biofire filmarray respiratory panel cptWebTerm: Qualifier: Evidence: With: Reference: Notes: Source: Original Reference(s) (-)-epigallocatechin 3-gallate : multiple interactions: ISO: RGD:1350944: 6480464 ... biofire filmarray pdfWebExopolyphosphatase PRUNE1 Gene PRUNE1 Source organism Homo sapiens (Human) go to search UniProt Q86TP1 go to UniProt Experimental structures None available in the PDB Biological function Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. biofire filmarray reagentsWebMar 2, 2024 · Functional modeling of NMIHBA-causing PRUNE1 variants reveals a requirement for its exopolyphosphatase activity. bioRxiv March 2, 2024 Caffey disease: new perspectives on old questions. biofire filmarray instrumentWebPRUNE1 is ubiquitously expressed across multiple tissues with widespread central nervous system expression during fetal development in humans ( 5 ). Previous studies have implicated PRUNE1 in a complex network of interactions regulating cell cycle and motility, with elevated PRUNE1 expression associated with cancer metastasis ( 6–8 ). daikin 12.5kw ducted priceWebOct 21, 2024 · The PRUNE1 gene encodes a member of the DHH phosphoesterase family, which are enzymes that hydrolyze phosphoester bonds of a broad spectrum of … daikin 12.5kw ducted air conditioner reviewWebMar 3, 2024 · exopolyphosphatase PRUNE1: CCP110: centriolar coiled-coil protein of 110 kDa: SEC16A: protein transport protein Sec16A: CRYBG3: very large A-kinase anchor protein: SPAG5: sperm-associated antigen 5: DCP1A: mRNA-decapping enzyme 1A: STON1: stonin-1: DCP1B: mRNA-decapping enzyme 1B: TRAK1: trafficking kinesin … biofire filmarray specs