WebJan 18, 2024 · Potential Drug Interactions. Firstly, pomelo contains a significant amount of furanocoumarin . Furanocoumarin is a compound found in some plants that inhibits the activity of an enzyme in the liver known as CYP3A4 (24, 25). CYP3A4 is the enzyme that metabolizes various drugs, including statins and antihypertensive (blood pressure) … WebJan 1, 2012 · The pomelo-tacrolimus interaction showed concentration dependency. Even low concentration of pomelo juice could enhance the blood concentrations of tacrolimus …
Fruit Interactions with Common Medicines - Medsafe
WebCitrus juices such as grapefruit juice (GFJ), orange, lemon, pomelo and lime were known to interact with cyclosporine in several randomized controlled trials. The present review is a systematic compilation and quantitative synthesis on the changes of cyclosporine pharmacokinetics with concomitant citrus juice administration. Web2 days ago · The purpose of our work is to describe the rationale and approach for creation and annotation of scientific corpus with information on food/drug interactions. This … daily minimum wage malta
Pomelo: Uses, Benefits, Side Effects By Dr. Smita Barode
WebPomelo mixes the sweet taste of orange with the tang of lemon. Its lineage means that pomelo contains many of the same compounds as grapefruit. One or more substances in … WebNov 10, 2024 · Food - drug interactions are well studied, however much less is known about cuisine - drug interactions. Non-native cuisines are becoming increasingly more popular as they are available in (almost ... WebOne whole grapefruit or 200 mL of grapefruit juice is sufficient to cause clinically relevant increased systemic drug concentration and subsequent adverse effects.11,12 Seville oranges, (often used in marmalades), limes and pomelos also produce this interaction.13–15 Varieties of sweet orange, such as navel or valencia, do not contain ... biological relationship in family