WebAquatic toxicology is a multidisciplinary field which integrates toxicology, aquatic ecology and aquatic chemistry. [1] This field of study includes freshwater, marine water and sediment environments. Common tests include standardized acute and chronic toxicity tests lasting 24–96 hours (acute test) to 7 days or more (chronic tests). Half maximal effective concentration (EC50) is a measure of the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time. More simply, EC50 can be defined as the concentration required to obtain a 50% [...] effect and may be … See more Biological responses to ligand concentrations typically follow a sigmoidal function. The inflection point at which the increase in response with increasing ligand concentration begins to slow is the EC50, which can be … See more A drug's potency is dependent on the drug's affinity and efficacy. Affinity Affinity describes … See more The effects of a stressor or drug generally depend on the exposure time. Therefore, the EC50 (and similar statistics) will be a function of exposure time. The exact shape of this time … See more • Determination of IC50 values See more The EC50 relates to the Hill equation, which is a function of the agonist concentration, [A]: where E is the observed response or effect above baseline, and … See more • Measures of pollutant concentration • Certain safety factor • LD50 (median lethal dose) See more
Toxic Units (TU) Indicators SpringerLink
Web4.1.1.3 Acute aquatic toxicity Acute aquatic toxicity would normally be determined using a fish 96 hour LC50 (OECD Test Guideline 203 or equivalent), a crustacea species 48 hour … WebNov 1, 2024 · Toxicity of propranolol very low (median EC50 6.64 mg/L) to all species in validated tests • Reports of very low concentrations causing effects must be shown to be repeatable. • Propranolol is concluded to be of very low risk to aquatic organisms. Abstract ovine leather是什么材质
Dose response: EC50, ED50, LD50 - Deranged Physiology
WebThe absolute EC50/IC50 should only be used if there are at least two assay concentrations whose predicted response is less than 50% and two whose predicted response is greater … WebVery toxic to aquatic organisms. Component Freshwater Algae Freshwater Fish Microtox Water Flea Sodium sulfate - Pimephales promelas: LC50: 13.5 - 14.5 g/L/96h - EC50: 4547 mg/L/96h EC50: 2564 mg/L/48h EC50: 4547 mg/L/96h Copper (II) sulfate pentahydrate (1:1:5) Not listed Onchorhynchus mykiss: LC50 = 0.1-2.5 mg/L/96h Photobacterium … WebA search was conducted for information on the chemical properties and toxicity of acetochlor to human health and to fish and aquatic life using the following databases and search ... water flea 48-h/EC50 7,200 1 AQUIRE Daphnia magna water flea 48-h/EC50 14,000 1 AQUIRE GMAV = 9,384.80 4. At least one benthic crustacean (e.g., ostracod, iso ... randymajors.org research hub